PRISM: Polymer, Recycling, Industrial, Sustainability and Manufacturing Institute (Midlands): Recent submissions
Now showing items 121-140 of 249
-
Production of polyhydroxybutyrate (PHB) and factors impacting its chemical and mechanical characteristics
(MDPI, 2020-12-04)Plastic pollution is fueling the grave environmental threats currently facing humans, the animal kingdom, and the planet. The pursuit of renewable resourced biodegradable materials commenced in the 1970s with the need for ... -
β-glucan metabolic and immunomodulatory properties and potential for clinical application
(MDPI, 2020-12-10)β-glucans are complex polysaccharides that are found in several plants and foods, including mushrooms. β-glucans display an array of potentially therapeutic properties. β-glucans have metabolic and gastro-intestinal effects, ... -
A bilayer vaginal tablet for the localized delivery of disulfiram and 5-fluorouracil to the cervix
(MDPI, 2020-12-06)This study was performed to develop an adjuvant therapy in the form of a self-administered vaginal tablet regimen for the localized delivery of chemotherapeutic drugs. This therapy will help to reduce relapse by eradicating ... -
Sustainable antimicrobial polymeric food packaging and anti-infection medical catheter preparation using antimicrobial peptide and Ag+ nanoreservoir formulations
(Athlone Institute of Technology, 2020-06)New antimicrobial interventions are urgently required to combat rising global health and medical infection challenges. Here, an innovative antimicrobial technology, providing price competitive alternatives to antibiotics ... -
Characterisation and in vivo evaluation of Araucaria angustifolia pinhão seed coat nanosuspension as a functional food source
(Royal Society of Chemistry, 2020-10-08)Araucaria angustifolia seeds are culturally important from South America; however, the seed coat is generally discarded and have yet to find a beneficial commercial impact. We propose a new formulation to the usage of ... -
Development of novel PVA-based nanoparticles for delivery system for bone cancer applications
(Athlone Institute of Technology, 2020-06)Osteosarcoma is one of the most frequent bone cancers with almost 30% of patients developin metastasis [1,2]. Further study is needed to develop new drugs that avoid metastasis. There is experimental evidence that chalcones, ... -
Yerba mate extract in microfibrillated cellulose and corn starch films as a potential wound healing bandage
(MDPI, 2020-11-27)Microfibrillated cellulose films have been gathering considerable attention due to their high mechanical properties and cheap cost. Additionally, it is possible to include compounds within the fibrillated structure in ... -
Development of a versatile monitoring technique for real-time protein activity tracking within cellular environment and biomimetic tissue engineering scaffold systems
(Athlone Institute of Technology, 2020-06)Crowded cellular environments with complex and intricate molecular interactions underpin biological processes. High biological noise is intrinsic within these biological systems, and this poses critical challenges to ... -
Production and testing of the flat faced tablets via overpriting of injection moulded tablet bases
(Athlone Institute of Technology, 2020-06)The pharmaceutical industry is exploring the realization of tailored dosage forms for individual patients to provide precision medicine. My supervisors have previously used a hybrid manufacturing technique that overmoulded ... -
"My heart, your heart"; hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded drug delivery system
(Athlone Institute of Technology, 2020-06)Cardiovascular diseases (CVDs) are the number 1 cause of death globally. Fenofibrate has been shown an excellent treating effect on CVDs. However, Fenofibrate is a neutral, lipophilic compound that is practically insoluble ... -
Long-term release rate of a nutritional supplement from a biodegradable polymer matrix
(Athlone Institute of Technology, 2020-06)For the purposes of ruminant nutrition, a 6-month timeframe is the ideal amount of time for the delivery of trace element and minerals. As a starting element, copper was chosen as it is the most commonly observed trace ... -
Antimicrobial films containing green synthesised zinc oxide nanoparticles for biomedical applications
(Athlone Institute of Technology, 2020-06)Synthetic biomaterials have been vastly investigated for different biomedical applications such as wound healing adhesives, implant devices and drug delivery systems. The effort on this field of study promoted the ... -
Development of novel polyethylene glycol dimethacrylate (PEGDMA)-based hydrogels for never regeneration
(Athlone Institute of Technology, 2020-06)Injury to the peripheral nervous system (PNS) affects more than 1,000,000 people worlwide a year. It is estimated that $150 billion is spent on nerve injury repair in the USA alone each year. The current surgical methods ... -
Hybrid manufacturing 3D printing and injection moulding in the pursuit of mass customization
(Athlone Institute of Technology, 2020-06)Project Overview: Mass customization is a marketing and manufacturing technique which combines the flexibility and personalization of custom-made products with the low unit costs associated with mass production. The ... -
Development of sustainable flexible packaging solutions using novel biodegradable and compostable polymer blends
(BioICEP, 2020-10-19)Plastic packaging has changed positively the way food products are delivered, reducing poverty and hunger due to the better protection of the goods, allowing their preservation for longer times throughout their supply ... -
Biodegradation and antimicrobial properties of zinc oxide-polymer composite materials for urinary stent applications
(MDPI, 2020-10-20)Research advancements in the field of urinary stents have mainly been in the selection of materials and coatings to address commonly faced problems of encrustation and bacterial adhesion. In this study, polylactic acid ... -
Development of a new bone scaffold for the treatment of large bone defects
(Athlone Institute of Technology, 2020-06)Large bone defects are typically caused by incidents such as fractures, diseases, trauma or surgeries. Worldwide more that 3/5 million bone grafts (either autografts or allografts) are performed each year. -
Evaluation of the efficacy of lipid core nanoemulsions containing temozolomide coupled to ferrocenes in the treatment of Glioblastomas
(Athlone Institute of Technology, 2020)Glioblastoma (GB) is the most common and aggressive neoplastic brain tumor, and its treatment has proved to be a challenge. For decades its therapy has been based on the use of temozolomide (TMZ), but the survival rate ... -
Development of smart 4-D materials utilising novel self assembly polymers
(2020-06)4D printing is a technique that uses a 3 D printer to create objects that change their shape overtime 4 D printing involves the use of smart materials that will transform when exposed to an external stimuli These can ... -
The development of novel bioresorbable medical devices for treating diseases of the anal canal
(Athlone Institute of Technology, 2020-06)Anal abscesses and fistulae in ano are the most prominent diseases of the anal canal Abscesses are pockets of pus caused by accumulating bactera whereas fistulae in ano are hollow tunnels that protrude from the wall of ...
