Now showing items 1-13 of 13
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Biodegradable medical implants
(De Gruyter, 2019) -
Development of a versatile monitoring technique for real-time protein activity tracking within cellular environment and biomimetic tissue engineering scaffold systems
(Athlone Institute of Technology, 2020-06)Crowded cellular environments with complex and intricate molecular interactions underpin biological processes. High biological noise is intrinsic within these biological systems, and this poses critical challenges to ... -
Development of dental implants with antimicrobial activity
(Technological University of the Shannon Midlands Midwest, 2022)Planktonic bacteria are capable of forming biofilms, which are described as microbial aggregates embedded within a matrix of extracellular polymeric substances (EPS) and are found attached to abiotic or biotic surfaces ... -
Development of electrospun PVA nanofibers via freeze-thawing method
(Athlone Institute of Technology, 2019)The polyvinyl alcohol (PVA) hydrogels are proven to have the benefits of improving water retention ability, cell attachment and controlled drug release in medical device materials for pharmaceutical applications. Due to ... -
Development of novel polyethylene glycol dimethacrylate (PEGDMA)-based hydrogels for never regeneration
(Athlone Institute of Technology, 2020-06)Injury to the peripheral nervous system (PNS) affects more than 1,000,000 people worlwide a year. It is estimated that $150 billion is spent on nerve injury repair in the USA alone each year. The current surgical methods ... -
The development of smart 4D materials using the smart temperature-sensitive polymer
(TUS Midlands Midwest, 2022)There is more that can be done with a 3D structure to make them more flexible and more useful: by utilising structures (Smart Polymers) that can transform in a preprogrammed way in response to a stimulus. Thus, giving ... -
Functionality of gold-edge-coated triangular silver nanoparticles in monitoring extracellular matrix protein conformations in C2C12/MC3T3-E1 culture in the presence of biomimetic bone tissue regeneration scaffolds
(TUS Midlands Midwest, 2022)In the cellular environment high noise levels can both mediate and interfere with cellular functions.The extracellular matrix (ECM) regulates protein dynamics and trajectories, which underpin critical biological ... -
Hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded delivery system
(TUS Midlands Midwest, 2022)Cardiovascular diseases (CVDs) are the number 1 cause of death globally. Fenofibrate has been shown an excellent treating effect on CVDs. However, Fenofibrate is a neutral, lipophilic compound that is practically insoluble ... -
Long-term release rate of a nutritional supplement from a biodegradable polymer matrix
(Athlone Institute of Technology, 2020-06)For the purposes of ruminant nutrition, a 6-month timeframe is the ideal amount of time for the delivery of trace element and minerals. As a starting element, copper was chosen as it is the most commonly observed trace ... -
"My heart, your heart"; hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded drug delivery system
(Athlone Institute of Technology, 2020-06)Cardiovascular diseases (CVDs) are the number 1 cause of death globally. Fenofibrate has been shown an excellent treating effect on CVDs. However, Fenofibrate is a neutral, lipophilic compound that is practically insoluble ... -
The osteoinduction of C2C12 myoblast cell-line treated with growth factor-incorporated biocomposites
(TUS Midlands Midwest, 2022)Bone regeneration scaffold serves as an alternative treatment to critical bone defects, substituting the traditional gold standard autologous bone grafting. A number of biomaterials and osteogenic growth factors are of ... -
Sustainable antimicrobial polymeric food packaging and anti-infection medical catheter preparation using antimicrobial peptide and Ag+ nanoreservoir formulations
(Athlone Institute of Technology, 2020-06)New antimicrobial interventions are urgently required to combat rising global health and medical infection challenges. Here, an innovative antimicrobial technology, providing price competitive alternatives to antibiotics ... -
Titanium-niobium alloys covered by electrospinning technique to applications in bone implants
(Athlone Institute of Technology, 2019)Recently, to avoid toxic metals in the human environment, there are many efforts to produce alloys containing titanium Ti and niobium Nb. Nb is a powerful stabilizer of beta-titanium phase[1]. Depending on the composition ...
