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Hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded delivery system

dc.contributor.authorYan, Guangming
dc.contributor.authorCao, Zhi
dc.contributor.authorDevine, Declan
dc.contributor.authorGately, Noel
dc.date.accessioned2022-02-14T10:20:51Z
dc.date.available2022-02-14T10:20:51Z
dc.date.copyright2022
dc.date.issued2022
dc.identifier.citationYan, G., Cao, Z., Devine, D., Gately, N. (2022). Hot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded delivery system. Presented at TUS MMW Poster Presentation Seminar January 2022en_US
dc.identifier.urihttp://research.thea.ie/handle/20.500.12065/3895
dc.description.abstractCardiovascular diseases (CVDs) are the number 1 cause of death globally. Fenofibrate has been shown an excellent treating effect on CVDs. However, Fenofibrate is a neutral, lipophilic compound that is practically insoluble in water, making it challenging to achieve therapeutic levels consistently. As a result, this project was using shellac material as the polymeric matrix to enhance the solubility of Fenofibrate by producing solid dispersion by hot melt extrusionen_US
dc.formatPDFen_US
dc.language.isoengen_US
dc.publisherTUS Midlands Midwesten_US
dc.rightsAttribution 4.0 International*
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/*
dc.subjectHot melten_US
dc.subjectDrug delivery systemen_US
dc.subjectTargeteden_US
dc.titleHot melt enteric targeted therapeutic delivery platform: enhancing drug solubility through advanced polymer extruded delivery systemen_US
dc.typeinfo:eu-repo/semantics/otheren_US
dc.contributor.affiliationAthlone Institute of Technologyen_US
dc.contributor.sponsorIrish Research Council (GOIPG/2018/2067) and Athlone Institute of Technology, Presidents Seed Fund.en_US
dc.identifier.orcidhttps://orcid.org/ 0000-0003-2765-682Xen_US
dc.identifier.orcidhttps://orcid.org/ 0000-0002-6638-8920en_US
dc.identifier.orcidhttps://orcid.org/ 0000-0002-1364-5583en_US
dc.identifier.orcidhttps://orcid.org/ 0000-0002-2610-2975en_US
dc.rights.accesshttps://creativecommons.org/licenses/by/4.0/
dc.rights.accessrightsinfo:eu-repo/semantics/openAccessen_US
dc.rights.accessrightsinfo:eu-repo/semantics/openAccess
dc.subject.departmentMaterials Research Institute AITen_US
dc.type.versioninfo:eu-repo/semantics/publishedVersionen_US


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Attribution 4.0 International
Except where otherwise noted, this item's license is described as Attribution 4.0 International