PRISM: Polymer, Recycling, Industrial, Sustainability and Manufacturing Institute (Midlands): Recent submissions
Now showing items 181-200 of 249
-
Electrospun natural polysaccharide for biomedical applications.
(Elsevier, 2019-07-27)Electrospinning is a simple and versatile technique in nanotechnology for fabricating nanofibers scaffolds for tissue regenerations, drug delivery systems, wound healing, and cancer therapy. This chapter provides a synopsis ... -
Comparison of fused-filament fabrication to direct compression and injection molding in the manufacture of oral tablets.
(Elsevier, 2019-03-10)Oral tablets are a convenient form to deliver active pharmaceutical ingredients (API) and have a high level of acceptance from clinicians and patients. There is a wide range of excipients available for the fabrication of ... -
Green synthesis of zinc oxide nanoparticles: a review of the synthesis methodology and mechanism of formation.
(Elsevier, 2020-03)Zinc oxide is of significant importance for many industries due to its versatile properties, which have been enhanced with the production of this material in the nanoscale. Nonetheless, the increase in concerns related to ... -
Orthopaedic 3D printing in orthopaedic medicine.
(Springer, 2019-09-17)Orthopaedic surgeries are commonly extremely challenging, and innovations are required to overcome a series of recognised difficulties and improve patient outcomes. Complications, in particular, the high occurrence of ... -
Analysis of the mechanical properties of solvent cast blends of PLA/PCL.
(Trans Tech Publications, 2014-09)Polylactic acid (PLA) is the most promising material in the biodegradable category. However, brittleness and poor thermal stability restrict its application. To overcome this limitation, PLA may be blended with other ... -
Stability studies of hot-melt extruded ternary solid dispersions of poorly-water soluble Indomethacin with Poly(vinyl pyrrolidone-co-vinyl acetate) and polyethylene oxide.
(Elsevier, 2019-08)This investigation aims to evaluate the effect of moisture and temperature on the physical stability and dissolution behaviour of hot-melt extruded binary and plasticised ternary solid dispersions. Poorly water-soluble ... -
3D printed polymers are less stable than injection moulded counterparts when exposed to terminal sterilization processes using novel vaporized hydrogen peroxide and electron beam processes.
(Elsevier, 2019-11-21)There is an increasing trend for use of 3D printing processes in healthcare due in part to emergence of customised medical devices and associated low manufacturing cost. However, there is a dearth of knowledge on the ... -
The effect of cooling on the degree of crystallinity, solid-state properties, and dissolution rate of multi-component hot-melt extruded solid dispersions.
(MDPI, 2020-03-01)The effect of cooling on the degree of crystallinity, solid-state and dissolution properties of multi-component hot-melt extruded solid dispersions [SD] is of great interest for the successful formulation of amorphous ... -
An investigation of the inter-molecular interaction, solid-state properties and dissolution properties of mixed Copovidone hot-melt extruded solid dispersions.
(Elsevier, 2019-10)Previous research has focused on spray dried quaternary mixtures which due to the addition of a surfactant 26 affected the physical stability and amorphous stability of selected model drugs. Very little research has 27 ... -
Additive manufacturing of PLA/HNT nanocomposites for biomedical applications
(Elsevier, 2019)Additive manufacturing has been of great interest of research in various applications due to their ease in processability, cost effectiveness and adaptability. In this study Poly Lactic Acid (PLA) was used as the base ... -
Processing stability and the significance of variation in extrusion speeds and temperture on SSB® 55 Pharma Grade Shellac for Oral Drug Delivery
(MDPI, 2017-09-06)The melt-extrusion process is utilized in the pharmaceutical arena for the manufacturing of a variety of dosage forms and formulations, including solid dispersions. This technology is considered an efficient and continuous ... -
Nanofillers can be used to enhance the thermal conductivity of commercially available SLA resins.
(Elsevier, 2019-06)Stereolithography (SLA) is a form of 3D printing technology used for the production parts and patterns in a layer by layer fashion. Traditionally, 3D printing has been used for the manufacture of prototypes, however it is ... -
Optimizing the hardness of SLA printed objects by using the neural netwok and genetic algorithm
(Elsevier, 2019-06)In the developing field of manufacturing, 3D printing is rapidly increasing the horizon of what is possible. However, the possibility of implementing new 3D methods of production has brought new challenges for industries, ... -
Enhancing the bioavailability of hydrophobic drugs using hot melt extrusion
(Athlone Institute of Technology, 2018-04-24)Many existing drugs (as well as new revelations) in the pharmaceutical industry bear a distinct disadvantage in the sense that they are not water soluble, displaying low bioavailability values and consequently a reduced ... -
3D printed end of arm tooling (EOAT) of a robotic arm
(Athlone Institute of Technology, 2018-04-24)This research furthers the practice of designing and manufacturing an EOAT for low weight applications by utilising additive manufacturing (“3D Printing”) techniques to decrease energy consumption via tool weight savings ... -
Degradable nanocomposites for fused filament fabrication applications.
(MDPI, 2018-05-09)There has been a substantial increase in the use and development of plastics over the last century. However, due to ever-diminishing petroleum feedstocks and growing concern for the environment, there has been a rise in ... -
Material considerations for fused-filament fabrication of solid dosage forms.
(MDPI, 2018-04-02)Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, ... -
Additive manufacturing of personalized pharmaceutical dosage forms via stereolithography.
(MDPI, 2019-12-03)The introduction of three-dimensional printing (3DP) has created exciting possibilities for the fabrication of dosage forms, paving the way for personalized medicine. In this study, oral dosage forms of two drug ... -
The influence of mechanical stretching and freeze-thaw processing on the properties of polyvinyl alcohol hydrogels for drug delivery applications
(Athlone Institute of Technology, 2018-04-24)The study describes the development of physically cross-linked polyvinyl alcohol (PVA) hydrogels using uniaxial orientation via freeze-thawing (F/T). Although cryogels have shown significant improvements in long-term ... -
Pathogen displacement during intermittent catheter insertion: a novel in vitro urethra model.
(Wiley, 2019-11-29)Aim: To develop a novel in vitro urethra model and use it to determine if insertion of an intermittent urinary catheter (IC) displaces pathogenic bacteria from the urethral meatus along the urethra. Methods: Displacement ...
