PRISM: Polymer, Recycling, Industrial, Sustainability and Manufacturing Institute (Midlands): Recent submissions
Now showing items 201-220 of 249
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Smart hydrogels: therapeutic advancements in hydrogel technology for smart drug delivery applications.
(Wiley, 2015-12)Hydrogels are a fusion of solid and liquid phases which closely mimic biological tissue. As such they have enormous potential for drug delivery systems as they are biocompatible and may be tailored to specific applications. ... -
Mechanical properties of anodic titanium films containing ions of Ca and P submitted to heat and hydrothermal treatment.
(Elsevier, 2016-12)Anodic oxidation is a technique widely used to improve the bioactivity of Ti surface. In this study, micro-arc oxidation (MAO) was used to obtain an anodic film incorporating Ca and P ions to evaluate the effect of heat ... -
Synthesis and in vivo behaviour of PVP/CMC/Agar hydrogel membranes impregnated with silver nanoparticles for wound healing applications.
(ACS, 2018)The field of wound healing has seen an increase in research activity in wound care and hydrogel-based dressings have been targeted as a solution for these applications. Hydrogels with silver nanoparticles can present many ... -
Development of high strength nanocomposite for biodegradable stents
(Athlone Institute of Technology, 2018-04-24)The use of biodegradable polymer materials are considered to be good alternatives in urology (Donohue et. al. 2018), cardiovascular (Brie et. al. 2016) and tracheal airway stenosis which provide support before it is absorbed ... -
Degradable polymer nanocomposites for fused filament fabrication applications
(Athlone Institute of Technology, 2018-04-24)The use of plastics in everyday life has increased dramatically during the course of the 20th and 21st century which is primarily due to the characteristics plastics offer in the development of new products to meet the ... -
Synthesis and in vivo evaluation of a scaffold containing wollastonite/β‐TCP for bone repair in a rabbit tibial defect model.
(Wiley Online Library, 2019-08-08)Scaffolds are models designed to aid the interaction between cells and extracellular bone matrix, providing structural support for newly formed bone tissue. In this work, wollastonite with β‐TCP porous ceramic scaffolds ... -
The development of a melt-extruded shellac carrier for the targeted delivery of probiotics to the colon.
(MDPI, 2017-12)Hot melt extrusion (HME) is considered an efficient technique in developing solid molecular dispersions, and has been demonstrated to provide sustained, modified and targeted drug delivery resulting in improved ... -
Influence of annealing and biaxial expansion on the properties of Poly-l-lactic) medical tubing.
(MDPI, 2019-07-11)Poly-l-lactic acid (PLLA) is one of the most common bioabsorbable materials in the medical device field. However, its use in load-bearing applications is limited due to its inferior mechanical properties when compared ... -
The influence of low shear microbore extrusion on the properties of high molecular weight poly(l-lactic acid) for medical tubing applications.
(MDPI, 2019-04)Biodegradable polymers play a crucial role in the medical device field, with a broad range of applications such as suturing, drug delivery, tissue engineering, sca olding, orthopaedics, and fixation devices. Poly-l-lactic ... -
Synthesis and characterisation of novel temperature and pH sensitive physically crosslinked poly(N-vinylcaprolactam-co-itaconic acid) hydrogels for drug delivery.
(MDPI, 2019-08-29)Previous studies involving poly N-vinylcaprolactam (PNVCL) and itaconic acid (IA) have synthesised the hydrogels with the presence of a solvent and a crosslinker, producing chemically crosslinked hydrogel systems. In this ... -
Vaginal drug delivery for the localised treatment of cervical cancer.
(Springer, 2017-06-08)Cervical cancer is usually treated by surgery, with the more advanced cancers requiring adjuvant chemotherapy or radiotherapy. The location of the cervix makes it easily accessible through the vagina for the localised ... -
Faster release of lumen-loaded drugs than matrix-loaded equivalent in polylactic acid/halloysite nanotubes.
(MDPI, 2019-06-15)Nanocomposite-based drug delivery systems with intrinsic controlled release properties are of great interest in biomedical applications. We report a novel polylactic acid (PLA)/halloysite nanotube (HNT) nanocomposite-based ... -
Preparation of biodegradable poltyethylene glycol dimethacrylate hydrogels via thiol-ene chemistry.
(MDPI, 2019-08-13)Through the control of the molecular weight, water content and monomer concentration, polyethylene glycol dimethacrylate (PEGDMA) based hydrogels have been adapted for numerous applications, including as structural scaffolds, ... -
Platelet-rich plasma, Hydroxyapatite, and Chitosan in the bone and cartilaginous regeneration of femoral trochlea in rabbits: clinical, radiographic, and histomorphometric evaluations.
(Hindawi, 2018-06)The aim of this study was to evaluate the trochlear bone and cartilaginous regeneration of rabbits using the association of PRP, chitosan, and hydroxyapatite. Hole was made in rabbit troches, one hole in each animal ... -
A tough and novel dual-response PAA/P(NiPAAM-co-PEGDMA) IPN hydrogels with ceramics by photopolymerization for consolidation of bone fragments following fracture.
(IOP Science, 2019-07)In this work, a novel dual-response hydrogel for enhanced bone repair following multiple fractures was investigated. The conventional treatment of multiple bone fracture consists on removing smaller bone fragments from the ... -
Investigation of a novel freeze-thaw process for the production of drug delivery hydrogels
(Springer, 2005-12)Poly(vinyl alcohol) (PVA) is a water-soluble, biocompatible and biodegradable polymer, which has been widely applied in biomedical fields. In this paper, novel physically cross-linked hydrogels composed of PVA and comprising ... -
Preparation of a novel freeze thawed poly (vinly alcohol) composite hydrogel for drug delivery applications
(Elsevier, 2007-09)Poly(vinyl alcohol) (PVA) is a water-soluble, biocompatible and biodegradable polymer, which has been widely applied in biomedical fields. In this paper, novel physically cross-linked hydrogels composed of PVA and comprising ... -
The production of a novel poly(vinyl alcohol) hydrogel cryogenic spheres for immediate release using a droplet system.
(IOP Science, 2019-06-05)Although freeze-thaw mechanism for producing crosslinked hydrogels is relatively easy and simple, it lacks sufficient integrity and support leading to modifications on its three-dimensional polymeric network arrangement ... -
Investigation of the effects of orientation on freeze/thawed Polyvinyl alcohol hydrogel properties.
(Elsevier, 2018-12)Although hydrogels produced via freeze-thawing (F/T) technique have been thoroughly studied in literature, stretching hydrogels in between freeze-thawing cycles could change its properties and might be modulated for drug ... -
Electrospun hydrogels composites for bone tissue engineering.
(Woodhead Publishing, 2019)Electrospinning is one of the foremost nanotechnology applications to fabricate bone tissue engineering scaffolds with sizes in the nanometer range. It is regarded as a versatile, inexpensive, and relatively simple methodology ...
